This shows that in patients with urinary tract infections, hematological parameters should be monitored : A Part from the Book Chapter : Evaluation of Uropathogenic Infections and Antibiotic Susceptibility Profiles of Bacteria in Patients at the CHU Ignace Deen National Hospital, Conakry (Republic of Guinea)

Urinary Tract Infection (UTI)

The distribution of patients with UI shows that out of 88 patients with urinary tract infections, 86 had a low hemoglobin level, i.e. 98%. Also, 13 patients had low lymphocyte counts, i.e. 15%, while 10 patients had low neutrophils, i.e. 11% and only one patient suffered from hypo-leukocytosis, i.e. 1%. On the other hand, 73 patients had high leukocyte levels, i.e. 83%. On the other hand, 76 patients had hyper-neutrophilia, i.e. 86% and 7 patients had high Mixed elements (Basophils, Eosinophils and Monocytes), i.e. 8%. This situation could be explained by the sepsis and the presence of other infections in the patients.

This shows that in patients with urinary tract infections, hematological parameters should be monitored.

Analysis of this table shows us that of the 88 patients with urinary tract infections, 86% had a low hemoglobin level with the following anemic typology: mild anemia in 27 patients (i.e. 31%), anemia moderate in 50 patients (i.e. 64%) and severe anemia in 9 patients (i.e. 10%).

These data show that in patients with urinary tract infections, the hemoglobin level should be monitored. In patients with severe and moderate anemia, this situation could be corrected by a good, rich and balanced diet, while in patients with severe anemia, it could be corrected by a blood transfusion before any antibiotic treatment.

Author(s) Details:

Taliby Dos Camara
Microbiology Laboratory, Department of Biology, Faculty of Sciences, and Gamal Abdel Nasser University of Conakry BP: 1147, Republic of Guinea.

Abdoulaye Makanera
Microbiology Laboratory, Department of Biology, Faculty of Sciences, and Gamal Abdel Nasser University of Conakry BP: 1147, Republic of Guinea and Biomedical Laboratory of the China-Guinea Friendship Hospital, Kipé, Cité des Médecins, Commune Ratoma 30 BP: 710 Conakry, Republic of Guinea.

Mounaida Rachid
Microbiology Laboratory, Department of Biology, Faculty of Sciences, and Gamal Abdel Nasser University of Conakry BP: 1147, Republic of Guinea and National Reference Laboratory for Mycobacteria at the CHU Ignace Deen in Conakry, Republic of Guinea.

Mory Camara
Biomedical Laboratory of the China-Guinea Friendship Hospital, Kipé, Cité des Médecins, Commune Ratoma 30 BP: 710 Conakry, Republic of Guinea.


Also See : Spread of Nongregarious Locust : A Part from the Book Chapter : Simulation of Favourable Habitats and Potential Spread for Non-gregarious Locust Pests for Preventive Measures in North Kazakhstan Based on Satellite Data


Recent Global Research Developments in Hematological Findings in Urinary Tract Infection Patients

 

Definitions of Urinary Tract Infection in Current Research: This systematic review highlights the heterogeneity in UTI definitions across studies. It emphasizes the need for a consensus-based research reference standard for UTI, considering various clinical signs, symptoms, and diagnostic tests [1].

Incidence of Urinary Tract Infection Among Patients: This meta-analysis found that the global pooled incidence of UTI is 1.6%, with the highest incidence reported in the African region at 3.6%. The study underscores the importance of implementing safety measures to reduce UTI incidence [2].

Prevention of Urinary Tract Infections in an Era of Antibiotic Resistance: This article discusses strategies to prevent UTIs, focusing on the challenges posed by antibiotic resistance. It suggests alternative approaches, including the use of probiotics and vaccines [3].

Recurrent Urinary Tract Infection Genetic Risk: This research identifies genetic variants associated with the risk of recurrent UTIs, such as those in the HLA-B, CXCR1, and TLR4 genes. These findings could lead to personalized treatment strategies for patients with recurrent UTIs [4].

New Strategy to Combat Urinary Tract Infections: Researchers have discovered a sequence of events during UTIs that balances bacterial elimination and tissue damage minimization. This insight could lead to new therapeutic approaches to manage UTIs more effectively [5].

References

  1. Manu P Bilsen, Rosa M H Jongeneel, Caroline Schneeberger, Tamara N Platteel, Cees van Nieuwkoop, Lona Mody, Jeffrey M Caterino, Suzanne E Geerlings, Bela Köves, Florian Wagenlehner, Simon P Conroy, Leo G Visser, Merel M C Lambregts, Definitions of Urinary Tract Infection in Current Research: A Systematic Review, Open Forum Infectious Diseases, Volume 10, Issue 7, July 2023, ofad332, https://doi.org/10.1093/ofid/ofad332
  2. Mengistu, D. A., Alemu, A., Abdukadir, A. A., Mohammed Husen, A., Ahmed, F., & Mohammed, B. (2023). Incidence of urinary tract infection among patients: systematic review and meta-analysis. INQUIRY: The Journal of Health Care Organization, Provision, and Financing, 60, 00469580231168746.
  3. Burrows LL (2024) It’s uncomplicated: Prevention of urinary tract infections in an era of increasing antibiotic resistance. PLoS Pathog 20(2): e1011930. https://doi.org/10.1371/journal.ppat.1011930
  4. Isali, I., Wong, T.R., Batur, A.F. et al. Recurrent urinary tract infection genetic risk: a systematic review and gene network analysis. Int Urogynecol J 35, 259–271 (2024). https://doi.org/10.1007/s00192-023-05671-6
  5. Research reveals potential new strategy to combat urinary tract infections
    https://www.sciencedaily.com/releases/2021/10/211019120103.htm

To Read the Complete Chapter See Here

Leave a Reply