Oxidative Stress Which Occurs as a Result of an Imbalance Between the Reactive Oxygen Species : A Part from the Book Chapter : Role of Matrix Metalloproteases and Total Antioxidant Capacity in Early Childhood Caries – A Review

children with ECC

Oxidative stress which occurs as a result of an imbalance between the reactive oxygen species [ROS] and antioxidants (AO) system has been implicated as one of the important contributory etiologic factors in many of the oral inflammatory pathologies and supposedly dental caries is no exception. When we compared the TAC of saliva in children with ECC and rampant caries (RC), the results suggest an increase in the TAC of saliva in children with caries be it ECC or RC indicating a linear relation between TAC of saliva and caries. It has been suggested that the levels of antioxidants could be altered in response to an infection or disease.

Author(s) Details:

Umapathy Thimmegowa,
Department of Pediatric and Preventive Dentistry, Raja Rajeswari Dental College and Hospital, No 14, Ramohalli Cross, Kumbalgodu, Mysore Road, Bengaluru-560074, India.

Soumya Pai,
Department of Pediatric and Preventive Dentistry, Raja Rajeswari Dental College and Hospital, No 14, Ramohalli Cross, Kumbalgodu, Mysore Road, Bengaluru-560074, India.

Praveen Malavalli Nagarajshetty,
Department of Orthodontics and Dentofacial Orthopaedics, KLE’ S Institute of Dental Sciences, Yeshwanthpur Suburb, Tumkur Road, Bengaluru- 560022, India.

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