compares lipid parameters in individuals with different blood pressures classified as normotensive, prehypertensive and hypertensive. Lipid parameters include high-density lipoprotein (HDL), low-density lipoprotein (LDL), total cholesterol (TCHOL), and triglycerides (TG). No differences were found in HDL, LDL, TCHOL or TG levels (all p>0.05). This shows that the lipid index of the participants in this study cannot change much depending on the blood pressure. Little change was observed in some parameters. For example, the hypertensive group appeared to have slightly higher HDL levels compared to the normotensive and prehypertensive groups, but this difference was not significant (p = 0.777). Similarly, LDL and TCHOL levels increased slightly in the hypertensive group, but these differences were not significant (p = 0.768 and p = 0.765, respectively). level (TG) showed a significant difference in the hypertensive group compared to the normotensive and prehypertensive groups, but this difference was not significant (p = 0.381). This finding contradicts the conventional belief that hypertension is associated with dyslipidemia, including high triglyceride levels. The measurements will have nothing to do with blood pressure. Although some lipids showed little difference from blood pressure, these differences did not reach significance. Factors other than blood lipids, such as genetic predispositions, lifestyle and metabolic factors, may also play an important role in determining the response to high blood pressure. Long-term follow-up to assess hypertension risk interactions, consideration of the potential for confounding variables, and changes in lipids over time associated with hypertension. Additionally, larger samples and more diverse studies will be needed to determine the relationship between lipid profile and hypertension in young people.
Author(s) Details:
Abena Sekyere
Department of Biochemistry, College of Science, Kwame Nkrumah University of Science and Technology, Ghana.
Recent Global Research Developments in Risk Factors for Hypertension in Young Adults: A Review
Early-Life Factors: Blood pressure (BP) in young adults is influenced by early-life factors, although the exact mechanisms remain unclear. BP tends to track strongly from adolescence into later life, emphasizing the importance of monitoring it early [1].
Cardiovascular Outcomes: Higher BP at a young age is associated with abnormalities in heart and brain imaging. It also increases the likelihood of cardiovascular events (such as coronary heart disease, heart failure, stroke, and transient ischemic attacks) later in life [1].
Lifestyle Interventions: Lifestyle changes can effectively lower BP initially, but sustaining these benefits beyond a few months remains challenging. Lifestyle interventions are crucial, but they require ongoing efforts to maintain blood pressure reduction [2].
Drug Treatment: While lifestyle modifications are essential, drug treatment may be necessary for some young adults with elevated BP. However, the pros and cons of drug therapy should be carefully considered [1].
Unique Considerations: Young women, especially during pregnancy, need specific advice on managing and treating BP. Pregnancy-related hypertension has implications for both the immediate health of the mother and the long-term health of their offspring [1].
References
- Hinton, T. C., Adams, Z. H., Baker, R. P., Hope, K. A., Paton, J. F., Hart, E. C., & Nightingale, A. K. (2020). Investigation and treatment of high blood pressure in young people: too much medicine or appropriate risk reduction?. Hypertension, 75(1), 16-22.
- Paul Leeson, Hypertension and cardiovascular risk in young adult life: insights from CAVI, European Heart Journal Supplements, Volume 19, Issue suppl_B, March 2017, Pages B24–B29, https://doi.org/10.1093/eurheartj/suw061
